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The current info panel design does not support enabling and disabling in game. You would have to save a flag for each panel to your saved variables file, then reload the UI and set the info panel's "enabled" flags in the ADDON_LOADED event so that nUI doesn't attempt to enable them.
nUI6 will change how info panels are loaded so it can be done in-game, for now howere you have to reload the UI to change that.
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