Not like the IGAS, the frames generate from the template class like Dialog, UIPanelButton is the same generated from the CreateFrame, there is no wrapper on them.
So there is no different to use them, you can use
button:SetScript("OnClick", function() end), or a better form:
button.OnClick = function(self) end.
Also the Style system can be used on the other ui elements that not generated by Scorpio:
Although there is no template class for them, so no skin, only custom settings.