After using the UI for a few weeks I have noticed a few glitches/oddities.
> DBM has bar issues. Half of the bars will be thick and others will be thin and it just looks messy.
> The focus bar overlaps the pet bar when you have the large layout enabled.
> The large layout has some positioning issues. I am running at 1920x1080 and I prefer the large layout, however I have to tinker with various positions of UI elements (namely cast bar elements slightly overlapping auras) and such. Also seems to cause DBM to bug out (as noted above).
I really love the UI after using TukUI/ElvUI (and variants) since WOTLK, here's hoping for even more improvements