It's possible to do something like this with KGpanels, but it only does artwork, now with reflux and Addon Control Panel, it would be much more possible, but it would still require you to switch profiles in ACP and reflux profiles, so it would be a pain in the ass, that's the only way you can do it, unless you want to make some form of bat file in windows to switch out your WTF/Interface folders that way. My suggestion, find a single UI like nUI or Lui or Spartan(not sure if it still exists) and learn to play everything with 1 UI, that's really the easiest thing to do. I personally make my own with KGpanels, but I've since quit wow, I will most likely release my UI's later though, I just don't know if I want anyone using my work just yet
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