If you want to move the target's casting bar in the HUD, then you would edit [ Interface > AddOns > nUI > Layouts > Default > HUDLayouts > PlayerTarget > nUI_HUDSkin_PlayerTarget_Target.lua ] and located the ["Casting"] section... same as before... modify the yOfs anchor element to move the casting bar up and down.
As for settings for alts... these changes that you're making to the layout apply to all of your toons. Options you set via slash commands are set on a per-toon basis.
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