[Yhor]

Thank you, I'll give that a try . I think my problem was anchoring and parenting to the same object (STUF target frame). I'll edit this post if it works (read, if I do it right).



Edit:
Bleh, been at it for a few, I'm sure I'm missing something, but whatever it is I fail to see it.

["Default"] = {
    -- This profile will be loaded on all characters.
    Viewport = { top = 0, bottom=130, left = 0, right = 0 },
    -- Art Container
    { name="Art", width="100%", height=250, bg_alpha=0, level=0 },
    -- Texture #1
    { name="Art1", parent="Art", tex_file="Bottom1.blp", bg_alpha=.95,
      anchor_to="LEFT", width="25%", height="100%" },
    -- Texture #2
    { name="Art2", parent="Art", tex_file="Bottom2.blp", bg_alpha=.95,
      anchor_to="RIGHT", anchor_from="CENTER", width="25%", height="100%" },
    -- Texture #3
    { name="Art3", parent="Art", tex_file="Bottom3.blp", bg_alpha=.95,
      anchor_to="LEFT", anchor_from="CENTER", width="25%", height="100%" },
    -- Texture #4
    { name="Art4", parent="Art", tex_file="Bottom4.blp", bg_alpha=.95,
      anchor_to="RIGHT", width="25%", height="100%" }
    -- Texture #5
    { name="Cave", anchor_frame="Stuf.units.target", tex_file="Cave.blp", bg_alpha=.95,
    level=0, anchor_to="CENTER", width="120", height="120" }
}

As you can see, I'm a newb (and have been away from addons for around 5 months (and WoW for that matter). Any help is greatly appreciated. When all of --Texture #5 is commented out (for the "Cave"), everything except the cave works, but as is, it kills all frames.