[Fizzlemizz]

Do you need to check for a buff? It seems you could alter the frames regardless of buff so long as you only do it once for each (assuming frame:CreateBeautyBorder creates a new frame each time)

Something more like:

-- This probalby only needs to run once at startup
TargetFrameHealthBarText:ClearAllPoints() 
TargetFrameHealthBarText:SetPoint("CENTER", TargetFrame, "CENTER", -50, 7)
TargetFrameManaBarText:SetScale(0.8)
 
local MaxReached
local function SkinTarget()
    if MaxReached then return end -- Why keep doing it
    if TargetFrame:IsShown() then
        for i = 1, MAX_TARGET_BUFFS do
            frame = _G["TargetFrameBuff" .. i]
            if not frame then break end
            if not frame.BeautyBorder then -- Have we adjusted this frame before?
                frame:CreateBeautyBorder(config.buff.bordersize)
                frame:SetBeautyBorderTexture(config.border.default)
                frame:SetScale(config.buff.scale)
                frame.BeautyBorder = true
                frameBorder = _G["TargetFrameBuff" .. i .. "Border"]
                frameCount = _G["TargetFrameBuff" .. i .. "Count"]
                frameBorder:Hide()
                frameCount:SetFont(config.font.atari, config.buff.fontsize, config.buff.outline)
                frameCount:SetPoint(unpack(config.buff.position))
                if i == MAX_TARGET_BUFFS then
                    MaxReached = true
                end
            end
        end
    end
end