I have not delved into all that Clique can do, so I may not be fully correct here.
From using it, I understand that you can only do ONE key combination. The combinations can't be different depending on the different frames.
For example:
I have Shift+Left-Click set to Lesser Healing Wave on my Restoration Shaman. When I do that combination on any unitframes I have (Party, Target, Player, etc.) it all does the same thing.
Maybe this is because I never looked hard enough that what you are talking about can be done, but that is what I know of.
I'm sorry if I was incorrect.
