http://www.wowace.com/addons/lock-smith/
makes a button that only shows up when you have locked things in your bags. repeatedly clicking it lockpicks everything.
I use a macro for applying poisons:
#showtooltip
/use [mod:shift] Deadly Poison; Instant Poison
/use [btn:1] 16; [btn:2] 17; [btn:3] 18
/click StaticPopup1Button1
Click is instant, shift+click is deadly.
Left click is main hand, right click is off hand, middle click is thrown.
So shift right click would put deadly only off hand.