It could be any number of mods depending on how old that screenshot is. However STUF and Pitbull can replicate that layout. That UF layout can also be done with oUF however unless you can find that layout, you will have to code it (in Lua), yourself.
The cast bar could anyone of a number of cast bar mods. eCastingBar, AzCastBar and Quartz can easily replicate the cast bar. oUF and STUF can also replicate the casting bar.